Massimo Minini opened his gallery in Brescia, dubbed Banco, in 1973. During his early years of activity, he was involved mainly with Conceptual Art, Arte Povera and Minimal Art.
He decided in the late seventies and early eighties to continue along these lines with works from some young Italian and foreign artists, including Ettore Spalletti, Jan Fabre, Didier Vermeiren, Bertrand Lavier, Anish Kapoor, Alberto Garutti, Icaro and Gerwald Rockenschaub. The gallery, however, also displayed works by figurative artists such as Salvo, Luigi Ontani, Ger Van Elk, Jiri Georg Dokoupil and Ryan Mendoza.
In the mid-1990s the gallery started to focus on a group of Italian artists, such as Eva Marisaldi, Mario Airò, Stefano Arienti, Maurizio Cattelan, Vanessa Beecroft, Sabrina Torelli, Sabrina Mezzaqui, Francesco Simeti and Paolo Chiasera. In more recent years, as well as displaying works by long-standing artists Boetti, Accardi, Fabro, Paolini, LeWitt, Barry, Graham and Buren the gallery has staged important exhibitions by Yona Friedman, Roger Ballen, Nedko Solakov, Haim Steinbach, Peter Halley and Ghada Amer, and works by newcomers such as Manfred Pernice, Sean Snyder, Mathieu Mercier, Jan De Cock, Tino Seghal, David Maljkovic, Haris Epaminonda, John Isaacs, Ariel Schlesinger.
Galleria Massimo Minini has stands at major international fairs, including Art Basel in Basel, Fiac in Paris, Artissima in Turin, Frieze in New York, and Miart in Milan.
In recent years the gallery has collaborated with a series of museums in Italy and abroad, one of its main achievements being a collection of Italian photographs entitled United Artists of Italy, which Massimo Minini put together and is currently touring several European museums. The collection comprises portraits of Italian artists by famous photographers such as Mulas, Giacomelli, Catalano, Gorgoni, Mussat Sartor and Cresci. He has loaned long-term to the Peggy Guggenheim Collection, Venice, a large sculpture by Anish Kapoor.